Aligning Discovery With Clinical Practice: Applying Expert Consensus Guidelines to Improve Patient Outcomes in CLL/SLL

December 5, 2025

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This activity's goal is to improve the knowledge, competence, and confidence of learners to integrate new and emerging therapies into practice to improve clinical outcomes in patients with chronic lymphocytic leukemia / small lymphocytic lymphoma.

Friday Satellite Symposium preceding the 67th ASH Annual Meeting and Exposition. 
Provided by the National Comprehensive Cancer Network in collaboration with Clinical Care Options, LLC

Target Audience

This educational activity is intended for hematologists, medical oncologists, physician associates, nurses, pharmacists, and other healthcare professionals who care for patients with chronic lymphocytic leukemia/small lymphocytic lymphoma.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Select individualized frontline therapy for patients with CLL/SLL, based on current evidence, recommendations outlined in NCCN Guidelines, expert guidance, and patient medical history and preferences
  • Plan optimal treatment strategies for patients with R/R CLL that integrate recommendations outlined in the NCCN Guidelines, emerging targeted therapy approaches, sequencing therapy based on response to and tolerance of prior therapy, and mechanisms of resistance
  • Devise comprehensive patient education and supportive care strategies for targeted therapy–associated AEs to improve clinical outcomes
Additional information
Supporters: 

Supported by educational grants from AstraZeneca and Lilly.

Course summary
Available credit: 
  • 2.00 AAPA Category 1 CME credit
  • 2.00 ACPE contact hours
  • 2.00 AMA PRA Category 1 Credit™
  • 2.00 ANCC contact hours
    • 1.50 ANCC Pharmacology Contact Hours
  • 2.00 Participation
Course opens: 
12/05/2025
Course expires: 
01/11/2026
Event starts: 
12/05/2025 - 7:00am EST
Event ends: 
12/05/2025 - 9:00am EST
Cost:
$0.00

Matthew Cortese, MD, MPH
Staff Physician and Assistant Professor of Oncology
Division of Hematology/Oncology
Department of Medicine
Lymphoma Section and Department of Cancer Genetics & Genomics
Roswell Park Comprehensive Cancer Center
Buffalo, New York

Brian Hill, MD, PhD
Director of the Lymphoid Malignancies Program
Associate Professor, Cleveland Clinic Lerner College of Medicine
Staff Physician
Department of Hematology & Medical Oncology
Cleveland Clinic Taussig Cancer Institute
Cleveland, Ohio

Sameer A. Parikh, MBBS
Consultant, Division of Hematology
Chair, CLL Disease Team
Vice Chair, Lymphoid Malignancies Disease Group
Mayo Clinic Comprehensive Cancer Center
Associate Professor of Medicine and Assistant Professor of Oncology
Mayo Clinic Alix School of Medicine and Science
Rochester, Minnesota

 

NCCN Continuing Education Disclosure Policy
It is the policy of NCCN that all planners, faculty, moderators, authors, reviewers and anyone involved in the planning and delivery of NCCN continuing education activities are expected to disclose ALL financial relationships they have had in the past 24 months with ineligible companies. The ACCME Standards for Integrity and Independence require that individuals who refuse to provide this information will be disqualified from involvement in the planning and implementation of accredited continuing education presented by NCCN. NCCN identifies, mitigates and discloses to learners all relevant financial relationships.

In addition, all content has been reviewed to ensure education promotes safe, effective patient care and does not promote the products or services of an ineligible company. Content, including any presentation of therapeutic options, is fair, balanced, evidence-based, scientifically accurate, and free of commercial bias and marketing. 

Definitions  

Ineligible Company: An ineligible company is any entity whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. 

Relevant Financial Relationships: Financial relationships of any dollar amount occurring within the past 24 months are defined as relevant if the educational content an individual can control is related to the business lines or products of an ineligible company. There is no minimum financial threshold. We ask for disclosure of ALL financial relationships with ineligible companies, regardless of the amount and regardless of the potential relevance of each relationship to the education.

Faculty Disclaimers  

All faculty for this continuing education activity are competent in the subject matter and qualified by experience, training, and/or preparation for the tasks and methods of delivery.

Faculty presentations may include discussion of off-label use. Faculty will disclose that the use in question is not currently approved by the FDA per the product labeling or marketing.

Faculty Disclosures

The faculty listed below has the following relevant financial relationships with ineligible companies to disclose.  All of the relevant financial relationships listed for these individuals have been mitigated.

Matthew Cortese, MD, MPH: consultant/advisor/speaker: AbbVie, AstraZeneca, Bristol Myers Squibb, Cellectar Biosciences, Secura Bio, Synthekine; researcher: Merck.

Brian Hill, MD, PhD: consultant/advisor/speaker: AbbVie, AstraZeneca, BeOne, Bristol Myers Squibb, Genentech, Pharmacyclics; researcher: AbbVie, AstraZeneca, BeOne, Bristol Myers Squibb, Genentech, Nurix, Pharmacylics.

Sameer A. Parikh, MBBS: researcher (paid to institution): AstraZeneca, Genentech, Janssen, Merck; consultant/advisor (paid to institution): AbbVie, AstraZeneca, BeiGene, Genentech, Janssen, Kite, Merck, MingSight, NovalGen, Pharmacyclics, Sobi.

NCCN/CCO Staff Disclosures

None of the other planners/managers for this educational activity have relevant financial relationships to disclose with ineligible companies whose primary business is producing, marketing, selling, reselling, or distributing healthcare products used by or on patients. 

In support of improving patient care, National Comprehensive Cancer Network (NCCN) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Physicians
NCCN designates this live activity for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses
NCCN designates this educational activity for a maximum of 2.0 contact hours. This activity offers 1.5 pharmacotherapeutic contact hours for nurses.

Pharmacists
NCCN designates this application-based continuing education activity for 2.0 contact hours (0.2 CEUs) of continuing education credit. UAN: JA4008196-0000-25-114-L01-P

PAs
NCCN has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 2.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.

American Board of Internal Medicine Maintenance of Certification (MOC)

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 2.0 medical knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregated participant data will be shared with the commercial supporters of this activity.

For ABIM MOC points, your information will be shared with the ABIM through NCCN's Joint Accreditation Program and Activity Reporting System (JA-PARS). Please allow 6-8 weeks for your MOC points to appear on your ABIM records.

By sharing your Diplomate Board ID # and DOB, you are giving NCCN permission to use this information/data to report your participation to ABIM via the Joint Accreditation Program and Activity Reporting System (JA-PARS).

Available Credit

  • 2.00 AAPA Category 1 CME credit
  • 2.00 ACPE contact hours
  • 2.00 AMA PRA Category 1 Credit™
  • 2.00 ANCC contact hours
    • 1.50 ANCC Pharmacology Contact Hours
  • 2.00 Participation

Price

Cost:
$0.00
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Required Hardware/software

To complete this activity, users will need:

  • A device with an Internet connection and sound playback capability
    • One of the two latest versions of Google Chrome, Mozilla Firefox, or Safari
    • Internet Explorer is no longer supported
  • Adobe Reader or other PDF reader software for certificate viewing/printing