Current Concepts in Penile Cancer

This review highlights the significant advances made in the diagnosis and management of penile cancer. This often-aggressive tumor phenotype has been characterized by its poor prognosis, mostly attributable to its late presentation and heterogeneity of surgical care because of the paucity of cases treated at most centers. Recent advances in understanding of the risk factors predisposing to penile cancer, including its association with the human papilloma virus (HPV), have brought forth the socioepidemiologic concept of HPV vaccination in certain high-risk populations and countries, which remains highly debated. The management of penile cancer has evolved in recent years with the adoption of penile-sparing and minimally invasive surgical approaches to the inguinal lymph nodes, which are a frequent site of regional spread for this malignancy. Lastly, this review highlights the importance of adopting a multimodal approach consisting of neoadjuvant systemic chemotherapy followed by consolidative surgical resection in patients presenting with bulky/locally advanced nodal metastases from penile cancer.

Target Audience

This activity has been designated to meet the educational needs of physicians and nurses involved in the management of patients with cancer.

Learning Objectives

Upon completion of this activity, participants will be able to:

  • Identify the risk factors associated with penile cancer
  • Discuss the rationale for adopting a multimodal approach consisting of neoadjuvant systemic chemotherapy followed by consolidative surgical resection in patients presenting with bulky/locally advanced nodal metastases from penile cancer
Additional information
Supporters: 

No commercial support was received for this article.

Course summary
Available credit: 
  • 1.00 Participation
  • 1.00 Nurse
  • 1.00 Physician
Course opens: 
05/13/2013
Course expires: 
05/13/2014
Cost:
$0.00

Philippe E. Spiess, MD
Department of Genitourinary Oncology
Moffitt Cancer Center
Tampa, Florida


Simon Horenblas, MD
Department of Urology
Netherlands Cancer Institute
Amsterdam, The Netherlands


Lance C. Pagliaro, MD
Department of Genitourinary Medical Oncology
The University of Texas MD Anderson Cancer Center
Houston, Texas


Matthew C. Biagioli, MD
Department of Radiation Oncology, Division of Brachytherapy
Moffitt Cancer Center
Tampa, Florida


Juanita Crook, MD
University of British Columbia
BCCA Center for the Southern Interior
British Columbia, Canada


Peter E. Clark, MD
Department of Urology
Vanderbilt University Medical Center
Nashville, Tennessee


Richard E. Greenberg, MD
Department of Urology
Fox Chase University
Philadelphia, Pennsylvania


Cesar E. Ercole, MD
Department of Genitourinary Oncology
Moffitt Cancer Center
Tampa, Florida

Available Credit

  • 1.00 Participation
  • 1.00 Nurse
  • 1.00 Physician

Accreditation Period

Course opens: 
05/13/2013
Course expires: 
05/13/2014

Price

Cost:
$0.00
Please login or register to take this course.

Required Hardware/software

To access this activity, users will need:

  • A device with an Internet connection
  • Adobe Reader or other PDF reader software for article and certificate viewing/printing