Brentuximab Vedotin in Patients With Relapsed HIV-Related Lymphoma

Lymphoma is a well-recognized complication in patients infected with HIV. Although its incidence has declined since the advent of antiretroviral therapy, it remains higher than in the general population. Several recent studies have noted improvement in clinical outcomes with the use of modern chemoimmunotherapy regimens. In patients who experience relapse, however, fewer data are available on the role of immunotherapy and its impact on outcomes. This case report presents 2 patients with relapsed HIV-associated lymphoma who experienced a second complete remission after treatment with the immunotherapy agent brentuximab vedotin.

Target Audience

This activity has been designated to meet the educational needs of physicians and nurses involved in the management of patients with cancer.

Learning Objectives

Upon completion of this activity, participants will be able to:

  • Describe the challenges associated with the management of patients with HIV-related lymphoma
  • Summarize the treatment options for patients with HIV-related lymphoma
  • Discuss the safety and efficacy of brentuximab vedotin in the treatment of patients with HIV-related lymphoma
Additional information
Supporters: 

No commercial support was received for this article.

Course summary
Available credit: 
  • 1.00 Participation
  • 1.00 Nurse
  • 1.00 Physician
Course opens: 
01/23/2014
Course expires: 
01/23/2015
Cost:
$0.00

Mitul Gandhi, MD
Northwestern University Feinberg School of Medicine
Robert H Lurie Comprehensive Cancer Center Department of Internal Medicine
Division of Hematology & Oncology
Chicago, Illinois

Adam Petrich, MD
Northwestern University Feinberg School of Medicine
Robert H Lurie Comprehensive Cancer Center Department of Internal Medicine
Division of Hematology & Oncology
Chicago, Illinois

Available Credit

  • 1.00 Participation
  • 1.00 Nurse
  • 1.00 Physician

Accreditation Period

Course opens: 
01/23/2014
Course expires: 
01/23/2015

Price

Cost:
$0.00
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Required Hardware/software

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  • A device with an Internet connection
  • Adobe Reader or other PDF reader software for article and certificate viewing/printing