Multimodality Approaches for the Curative Treatment of Esophageal Cancer

Carcinoma of the esophagus and gastroesophageal junction tumors presenting with locoregional disease are potentially curable, although the cure rate is modest. Many different treatment approaches have been studied, with a multimodality approach associated with a 10% to 15% greater survival advantage compared with a single-modality approach. A systematic review was conducted to address 3 clinical questions: whether patients with resectable esophageal cancer should receive preoperative versus postoperative therapy, how to choose between these options, and whether surgery be avoided in patients who are candidates for both definitive chemoradiotherapy and definitive combined modality therapy. Recommendations from 3 recent treatment guidelines from Ontario, NCCN, and Belgium were consulted to address these questions.

Target Audience

This activity has been designated to meet the educational needs of physicians and nurses involved in the management of patients with cancer.

Learning Objectives

Upon completion of this activity, participants will be able to:

  • Discuss the clinical evidence supporting the use of combined modality therapy for localized carcinoma of the esophagus and GEJ
  • Summarize the recommendations outlined in the clinical practice guidelines for the management of patients with localized resectable esophageal and GEJ
Additional information
Supporters: 

No commercial support was received for this article.

Course summary
Available credit: 
  • 1.00 Participation
  • 1.00 Nurse
  • 1.00 Physician
Course opens: 
02/18/2015
Course expires: 
02/18/2016
Cost:
$0.00

Raymond Jang, MD, MSc, FRCPC
Department of Medical Oncology
Princess Margaret Cancer Center
University Health Network, University of Toronto
Toronto, Ontario, Canada

Gail Darling, MD, FRCS
Department of Thoracic Oncology
Princess Margaret Cancer Center
University Health Network, University of Toronto
Toronto, Ontario, Canada

Rebecca KS Wong, MBChB, MSc, FRCPC
Department of Radiation Oncology
Princess Margaret Cancer Center
University Health Network, University of Toronto
Toronto, Ontario, Canada

Available Credit

  • 1.00 Participation
  • 1.00 Nurse
  • 1.00 Physician

Accreditation Period

Course opens: 
02/18/2015
Course expires: 
02/18/2016

Price

Cost:
$0.00
Please login or register to take this course.

Required Hardware/software

To access this activity, users will need:

  • A device with an Internet connection
  • Adobe Reader or other PDF reader software for article and certificate viewing/printing