This educational initiative addresses healthcare professionals’ need to be educated on practice-changing developments in the management of advanced genitourinary cancers that have taken center stage in recent years. The expansion of treatment options has improved patient care but has presented numerous clinical challenges.  For example, despite significant improvements in responses and survival with the use of TKIs and mTOR inhibitors as first-line therapy in patients with RCC, progression is universal in these patients. This underscores the need to understand optimal second-line therapy, optimal sequence of therapies, and novel treatment approaches such as immunotherapeutics that are currently in various phases of clinical development.

Metastatic prostate cancer has seen rapid expansion of therapeutic options, and, therefore, clinicians managing these patients are challenged to acquire, comprehend, and integrate the latest clinical evidence and recommendations. Additionally, prostate cancer and its treatments are associated with a diverse array of possible symptoms that can have a large negative impact on men’s quality of life both during and after treatment. Clinicians need to be updated on management strategies for the most common and troubling symptoms, including important novel treatments for patients with bone metastases that can improve bone health and prolong survival.

Although the standard of care for the treatment of advanced bladder cancer has remained mostly unchanged over the last 30 years, clinical trial data continue to provide insight into potential new therapies. The use of bladder-preserving strategies has improved quality of life, and newer agents that include molecularly targeted therapies and immunotherapies may further improve patient outcomes.