Management of EGFR-Mutation Positive Metastatic Non-Small Cell Lung Cancer

This information was originally presented at the NCCN 21st Annual Conference: Advancing the Standard of Cancer Care™ held in Hollywood, Florida, from March 31 – April 2, 2016.

Target Audience

This activity is designed to meet the educational needs of medical, surgical, and radiation oncologists; nurses; physician assistants; pharmacists; pathologists; and other healthcare professionals who manage patients with cancer.

Learning Objectives

Following this activity, participants should be able to:

  • Identify the different agents that can be used to treat patients with advanced non-small cell lung cancer (NSCLC) who have sensitizing EGFR mutations
Additional information
Supporters: 

These activities are supported by educational grants from AstraZeneca; BTG; Celgene Corporation; Clovis Oncology; Genentech; Genomic Health, Inc.; Gilead Sciences, Medical Affairs; Lilly; Merrimack Pharmaceuticals, Inc.; Novartis Oncology; Pfizer; Pharmacyclics LLC, an AbbVie Company and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC; Taiho Oncology; Takeda Oncology; and TESARO. These activities are supported by educational funding provided by Amgen. These activities are supported by an independent medical education grant from Bristol-Myers Squibb. These activities are supported by independent educational grants from AbbVie; Astellas and Medivation, Inc.; Boehringer Ingelheim Pharmaceuticals, Inc.; Incyte; and Merck.

Course summary
Available credit: 
  • 0.75 ACPE contact hours
  • 0.75 AMA PRA Category 1 Credit™
  • 0.80 ANCC contact hours
  • 0.75 Participation
Course opens: 
05/27/2016
Course expires: 
03/01/2017
Cost:
$0.00

Leora Horn, MD, MSc
Vanderbilt-Ingram Cancer Center

Rogerio Lilenbaum, MD
Yale Cancer Center/Smilow Cancer Hospital

 

Disclosure of Relevant Financial Relationships
All faculty and activity planners participating in NCCN continuing education activities are expected to disclose any relevant financial relationships with a commercial interest as defined by the ACCME’s, ANCC’s, and ACPE’s Standards for Commercial Support. All faculty presentations have been reviewed for adherence to the ACCME’s Criterion 7: The provider develops activities/educational interventions independent of commercial interests (SCS 1, 2, and 6) by experts on the topics.

The faculty listed below have disclosed the following relevant financial relationships:

Leora Horn, MD, MSc
AstraZeneca Pharmaceuticals LP: Grant/Research Support
Bayer HealthCare: Scientific Advisor
Biodesix, Inc.: Product/Speakers Bureau
Boehringer Ingelheim GmbH: Scientific Advisor
Bristol-Myers Squibb Company: Scientific Advisor
Genentech, Inc.: Consulting Fees, Honoraria
Merck & Co., Inc.: Consulting Fees, Honoraria
Xcovery: Scientific Advisor

Rogerio Lilenbaum, MD
Boehringer Ingelheim GmbH: Scientific Advisor
Celgene Corporation: Grant/Research Support; Scientific Advisor
Genentech, Inc.: Scientific Advisor
Incyte Corporation: Scientific Advisor
Verastem, Inc.: Scientific Advisor

NCCN Staff Disclosures
The activity planning staff listed below has no relevant financial relationships to disclose:
Robert W. Carlson, MD; Ann Gianola, MA; Mark Geisler; Kristina M. Gregory, RN, MSN, OCN; Kristin Kline Hasson; Rose Joyce; Joan S. McClure, MS; Diane McPherson; Melanie Moletzsky; Deborah Moonan, RN, BSN; Lisa Perfidio; Liz Rieder; Shannon K. Ryan; Kathy Smith; Jennifer McCann Weckesser

The activity planning staff listed below has disclosed the following relevant financial relationships:

Mercedes De La Hoz
Pfizer Inc.: Other financial benefit

The NCCN clinical information team listed below, who have reviewed content, has no relevant financial relationships to disclose:
Miranda Hughes, PhD

The ACCME/ANCC/ACPE defines “conflict of interest” as when an individual has an opportunity to affect CE content about products or services of a commercial interest with which he/she has a financial relationship.

ACCME, ACPE, and ANCC focuses on financial relationships with commercial interests in the 12-month period preceding the time that the individual is being asked to assume a role controlling content of the CE activity. ACCME, ACPE, and ANCC have not set a minimal dollar amount for relationships to be significant. Inherent in any amount is the incentive to maintain or increase the value of the relationship. The ACCME, ACPE, and ANCC defines “’relevant’ financial relationships” as financial relationships in any amount occurring within the past 12 months that create a conflict of interest.

All faculty for this continuing education activity are competent in the subject matter and qualified by experience, training, and/or preparation to the tasks and methods of delivery.

Faculty presentations may include discussion of off-label use. Faculty will disclose that the use in question is not currently approved by the FDA per the product labeling.

Physicians
National Comprehensive Cancer Network (NCCN) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education to physicians.

National Comprehensive Cancer Network designates this activity for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Release date: May 27, 2016
Expiration date: March 1, 2017

Nurses
National Comprehensive Cancer Network (NCCN) is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s (ANCC) Commission on Accreditation. NCCN designates this educational activity for a maximum of 0.80 contact hours. Accreditation as a provider refers to the recognition of educational activities only; accredited status does not imply endorsement by NCCN or ANCC of any commercial products discussed/displayed in conjunction with the educational activity.

Kristina M. Gregory, RN, MSN, OCN, is our lead nurse planner for this educational activity.

Release date: May 27, 2016
Expiration date: March 1, 2017

Pharmacists

National Comprehensive Cancer Network is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

Type of Activity: Knowledge 

National Comprehensive Cancer Network designates this continuing education activity for 0.75 contact hour(s) (0.075 CEUs) of continuing education credit in states that recognize ACPE accredited providers.

Universal Activity Number: 0836-0000-16-068-H01-P

Release date: May 27, 2016
Expiration date: March 1, 2017

Available Credit

  • 0.75 ACPE contact hours
  • 0.75 AMA PRA Category 1 Credit™
  • 0.80 ANCC contact hours
  • 0.75 Participation

Price

Cost:
$0.00
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Required Hardware/software

To complete this activity, users will need:

  • A device with an Internet connection and sound playback capability
  • Adobe Flash Player and/or an HTML5 capable browser for video or audio playback
  • Adobe Reader or other PDF reader software for certificate viewing/printing