Screening, Diagnosis, and Management of Hereditary Renal Cell Carcinoma
Hereditary renal cell carcinoma (RCC) is a rare but complex and heterogeneous disease, and genetic testing, screening and surveillance, and treatment options vary according to the patient’s personal and/or family history of a hereditary RCC syndrome and/or clinical diagnosis of RCC. Because of hereditary RCC’s rarity, there is an overall lack of recommendations for diagnosing and managing patients who are suspected or confirmed to have the disease. However, because some hereditary RCC syndromes may be aggressive, it is important to effectively diagnose and manage patients as early as possible to limit associated morbidity and mortality.
The program is designed to meet the needs and improve the competence and performance of the interprofessional oncology care team, including physicians, nurse practitioners, nurses, physician assistants, pharmacists, and other relevant health care professionals who manage the care of patients with cancer.
Following this program, participants should be able to:
- Identify the most common hereditary RCC syndromes and their clinical features.
- Discuss screening and surveillance strategies for patients with a confirmed hereditary RCC syndrome.
- Review treatment options for patients with a confirmed hereditary RCC syndrome.
Shawna L. Boyle, MD
Fred & Pamela Buffett Cancer Center
Eric Jonasch, MD
The University of Texas MD Anderson Cancer Center
Brandon Manley, MD
Moffitt Cancer Center
NCCN Continuing Education Disclosure Policy
It is the policy of NCCN that every 12 months, all faculty, moderators, activity planners and all internal planning staff participating in NCCN continuing education activities are expected to disclose any financial relationships with a commercial interest. In addition, all faculty presentations have been reviewed to ensure education is fair and balanced and that clinical content presented supports safe, effective patient care. Individuals who do not disclose relevant financial relationships will be disqualified from involvement in the CE activity as a content developer, planner, or presenter.
NCCN continuing education considers financial relationships to create a conflict of interest when an individual has both a financial relationship with a commercial interest and the opportunity to affect continuing education content about the products or services of a commercial interest with which he/she has a financial relationship.
NCCN continuing education considers relevant financial relationships as financial relationships in any amount occurring within the past 12 months that create a conflict of interest. NCCN does not set a minimal dollar amount for relationships to be significant. Inherent in any amount is the incentive to maintain or increase the value of the relationship.
All faculty for this continuing education activity are competent in the subject matter and qualified by experience, training, and/or preparation for the tasks and methods of delivery.
Faculty presentations may include discussion of off-label use. Faculty will disclose that the use in question is not currently approved by the FDA per the product labeling.
The faculty listed below discloses no relevant financial relationships:
Shawna L. Boyle, MD
The faculty listed below discloses the following relevant financial relationships:
Eric Jonasch, MD
Aravive, Inc.: Grant/Research Support; Honoraria
Calithera Biosciences, Inc.: Honoraria
Eisai Inc.: Honoraria
Exelixis Inc.: Grant/Research Support; Honoraria
Genentech, Inc.: Honoraria
Merck & Co., Inc.: Grant/Research Support; Honoraria
NiKang Therapeutics, Inc.: Honoraria
Novartis Pharmaceuticals Corporation: Grant/Research Support; Honoraria
Pfizer Inc.: Grant/Research Support; Honoraria
Roche Laboratories, Inc.: Honoraria
Brandon Manley, MD
Merck & Co., Inc.: Consulting Fee
NCCN Staff Disclosures
The NCCN Leadership listed below discloses no relevant financial relationships:
Robert W. Carlson, MD; Wui-Jin Koh, MD; Gary J. Weyhmuller, MBA, SPHR
The NCCN Activity Planning staff listed below discloses no relevant financial relationships:
Mike Abrams; Melissa Esplen; Mark A. Geisler; Kristina M. Gregory, RN, MSN, OCN; Kristin Kline Hasson; Rose Joyce; Karen Kanefield; Lisa Perfidio, MS; Shannon Ryan, CMP; Kathy Ann Smith, CHCP; Sarah Weinstein
The NCCN Clinical staff listed below discloses no relevant financial relationships:
Mary A. Dwyer, MS, CGC; Liz Hollinger, RN, BSN; Angela D. Motter, PhD
In support of improving patient care, National Comprehensive Cancer Network (NCCN) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
NCCN designates this live activity for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
NCCN designates this educational activity for a maximum of 1.25 contact hours.
NCCN designates this application-based continuing education activity for 1.25 contact hours (0.125 CEUs) of continuing education credit. UAN: JA4008196-0000-21-056-H01-P
NCCN has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.25 AAPA Category 1 CME credits. Approval is valid until March 1, 2022. PAs should only claim credit commensurate with the extent of their participation.
- 1.25 AAPA Category 1 CME credit
- 1.25 ACPE contact hours
- 1.25 AMA PRA Category 1 Credit™
- 1.25 ANCC contact hours
- 1.25 Participation
To complete this activity, users will need:
- A device with an Internet connection and sound playback capability
- One of the two latest versions of Google Chrome, Mozilla Firefox, or Safari
- Internet Explorer is no longer supported
- Adobe Reader or other PDF reader software for certificate viewing/printing