Neuroradiologic evaluation, an important part of diagnosis and evaluation of the effectiveness of subsequent therapy, can be confounded by steroids administration used to alleviate symptoms of primary central nervous system lymphomas (PCNSL).

As a result of advances in diagnosis and treatment, many patients with brain metastases improve with proper management and do not die of progression from these metastatic lesions.

Development of new imaging and radiotherapy techniques available only at some facilities has led to a greater heterogeneity in treatment of meningioma across cancer care institutions.

For many years, the diagnosis and classification of gliomas have been based on histology. Although studies including large populations of patients demonstrated the prognostic value of histologic phenotype, variability in outcomes within histologic groups limited the utility of this system.

This information was originally presented at the NCCN 21^st Annual Conference: Advancing the Standard of Cancer Care™ held in Hollywood, Florida, from March 31 – April 2, 2016.