Optimizing Treatment for Head and Neck Cancers
Deintensification treatment protocols for HPV-associated locally advanced oropharyngeal cancer are being investigated in ongoing clinical trials. It is unclear whether to administer chemotherapy to patients with locoregionally advanced nasopharyngeal cancer (NPC) before or after systemic therapy/RT. Despite the ambiguities of PD-L1 testing and definitions, PD-L1 expression may be associated with better outcomes from treatment with immunotherapy for recurrent or metastatic head and neck squamous cell carcinoma (HNSCC).
Target Audience
This educational program is designed to meet the educational needs of physicians/oncologists, nurse practitioners, nurses, physician assistants, pharmacists, and other health care professionals who manage patients with cancer.
Learning Objectives
Following this program, participants should be able to:
- Describe deintensification strategies under investigation for HPV-associated locally advanced oropharyngeal cancer.
- Compare and contrast recommended treatment options for both locally advanced and recurrent/metastatic nasopharyngeal cancer.
- Identify immunotherapy options for patients with recurrent or metastatic head and neck squamous cell carcinoma.
Robert I. Haddad, MD
Dana-Farber Cancer Institute
David G. Pfister, MD
Memorial Sloan Kettering Cancer Center
Nadeem Riaz, MD, MSc
Memorial Sloan Kettering Cancer Center
NCCN Medical Education Disclosure Policy
It is the policy of NCCN that every 12 months, all faculty, moderators, activity planners and all internal planning staff participating in NCCN continuing education activities are expected to disclose any financial relationships with a commercial interest as defined by the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support. In addition, all faculty presentations have been reviewed for adherence to the ACCME’s Standards for Commercial Support (the provider develops activities/educational interventions independent of commercial interests [SCS 1, 2 and 6] by experts on the topics).
Per the ACCME Standards for Commercial Support, individuals who do not disclose relevant financial relationships will be disqualified from involvement in the CE activity as a content developer, planner, or presenter. A complete list of individuals’ relationships with external entities is available upon request.
Definitions
NCCN continuing education considers financial relationships to create a “conflict of interest” when an individual has both a financial relationship with a commercial interest and the opportunity to affect CE content about the products or services of a commercial interest with which he/she and/or a spouse or partner has a financial relationship.
NCCN continuing education considers “relevant financial relationships” as financial relationships in any amount occurring within the past 12 months that create a conflict of interest. NCCN does not set a minimal dollar amount for relationships to be significant. Inherent in any amount is the incentive to maintain or increase the value of the relationship.
Faculty Disclaimers
All faculty for this continuing education activity are competent in the subject matter and qualified by experience, training, and/or preparation for the tasks and methods of delivery.
Faculty presentations may include discussion of off-label use. Faculty will disclose that the use in question is not currently approved by the FDA per the product labeling.
Faculty Disclosures
The faculty listed below discloses the following relevant financial relationships:
Robert I. Haddad, MD
AstraZeneca Pharmaceuticals LP: Grant/Research Support; Consulting Fee
Bristol-Myers Squibb Company: Grant/Research Support; Consulting Fee
Celgene Corporation: Consulting Fee
Eisai Inc.: Consulting Fee
Genentech, Inc.: Grant/Research Support; Consulting Fee
Loxo Oncology: Grant/Research Support; Consulting Fee
Merck & Co., Inc.: Grant/Research Support; Consulting Fee
Pfizer Inc.: Grant/Research Support; Consulting Fee
David G. Pfister, MD
Atara: Grant/Research Support
Merck & Co., Inc.: Grant/Research Support
Nadeem Riaz, MD, MSc
Bristol-Myers Squibb Company: Grant/Research Support
Illumina: Consulting Fee
Pfizer Inc.: Grant/Research Support
REPARE Therapeutics: Grant/Research Support; Consulting Fee
NCCN Staff Disclosures
The NCCN Activity Planning staff listed below discloses no relevant financial relationships:
Robert W. Carlson, MD; Melissa Esplen; Mark A. Geisler; Kristina M. Gregory, RN, MSN, OCN; Kristin Kline Hasson; Rose Joyce; Karen Kanefield; Lisa Perfidio, MS; Shannon Ryan, CMP; Kathy Ann Smith, CHCP; Sarah Weinstein; Gary J. Weyhmuller, MBA, SPHR
The NCCN Activity Planning staff listed below discloses the following relevant financial relationships:
Wui-Jin Koh, MD
IBM Watson Health for Oncology and Genomics; Scientific Advisor
The NCCN Clinical staff listed below discloses no relevant financial relationships:
Jennifer L. Burns, BS; Susan D. Darlow, PhD; Rashmi Kumar, PhD
In support of improving patient care, National Comprehensive Cancer Network (NCCN) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physicians
NCCN designates this enduring material for a maximum of 1.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nurses
NCCN designates this educational activity for a maximum of 1.50 contact hours.
Pharmacists
NCCN designates this knowledge-based continuing education activity for 1.50 contact hours (0.150 CEUs) of continuing education credit. UAN: JA4008196-0000-20-093-H01-P
Physician Assistants
NCCN has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.50 AAPA Category 1 CME credits. Approval is valid until March 1, 2021. PAs should only claim credit commensurate with the extent of their participation.
Available Credit
- 1.50 AAPA Category 1 CME credit
- 1.50 ACPE contact hours
- 1.50 AMA PRA Category 1 Credit™
- 1.50 ANCC contact hours
- 1.50 Participation
Price
Required Hardware/software
To complete this activity, users will need:
- A device with an Internet connection
- One of the two latest versions of Google Chrome, Mozilla Firefox, or Safari (Internet Explorer is no longer supported)
- Adobe Flash Player and/or an HTML5 capable browser for video or audio playback
- Adobe Reader or other PDF reader software for certificate viewing/printing