NCCN Pharmacy Updates: Emerging Strategies in the Treatment of Venous Thromboembolism

December 23, 2020

Expanded indications for the use of the direct oral anticoagulants demand diligent monitoring. Health care professionals play a crucial role in the management of anticoagulation in cancer patients and anticoagulation monitoring clinics may need to rechannel resources to include these agents.  There is limited data in regards to Heparin Induced Thrombocytopenia in cancer patients and clinicians rely on evidence and consensus based guidelines to guide therapeutic decisions for acute and chronic treatment of venous thromboembolic disease in patients who experience this drug-induced toxicity. Most of the data heretofore for the use of the DOACs in patients with cancer has been from subgroup analysis. A growing body of evidence suggest that these agents can be used safely and effectively for both prophylaxis and treatment of VTE. Randomized clinical trial data evaluating the safety and efficacy of the DOACs versus low molecular weight heparin in patients with cancer have been published or are ongoing and a review of the available data will be beneficial to health care professionals.

Target Audience

This educational program is designed to meet the educational needs of pharmacists, physicians, nurses, nurse practitioners, physician assistants and other health care professionals who manage patients with cancer.

Learning Objectives

Following this activity, participants should be able to:

  • Interpret the recent prospective clinical data surrounding the use of DOACs in both the prevention and treatment of VTE in cancer patients. 
  • Show the expanded indications, efficacy, and safety for use of the direct oral anticoagulants (DOACs) in patients with cancer. 
  • Apply the 4Ts scoring system for identifying a patients risk for Heparin Induced Thrombocytopenia (HIT) and the use of HIT antibody and other diagnostic immunoassays in the clinical setting. 
Additional information
Supporters: 

This activity is supported by an educational grant:

  • AstraZeneca
  • Celgene Corporation
  • Coherus Biosciences
  • Novartis
  • Servier Pharmaceuticals, LLC

This activity is supported by an independent educational grant from:

  • AbbVie

This activity is supported by an independent medical education grant from:

  • Advanced Accelerator Applications, a Novartis company
  • Mylan Inc.

This educational activity is supported by a medical education grant from:

  • Exelixis, Inc.
Course summary
Available credit: 
  • 1.00 AAPA Category 1 CME credit
  • 1.00 ACPE contact hours
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 ANCC contact hours
  • 1.00 Participation
Course opens: 
06/08/2020
Course expires: 
03/07/2021
Event starts: 
12/23/2020 - 1:30pm
Event ends: 
12/23/2020 - 2:30pm
Cost:
$0.00

Cynthia Herrera, PharmD, BCPS, BCOP
Robert H. Lurie Comprehensive Cancer Center of Northwestern University

 

NCCN Medical Education Disclosure Policy
It is the policy of NCCN that every 12 months, all faculty, moderators, activity planners and all internal planning staff participating in NCCN continuing education activities are expected to disclose any financial relationships with a commercial interest as defined by the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support. In addition, all faculty presentations have been reviewed for adherence to the ACCME’s Standards for Commercial Support (the provider develops activities/educational interventions independent of commercial interests [SCS 1, 2 and 6] by experts on the topics). 

Per the ACCME Standards for Commercial Support, individuals who do not disclose relevant financial relationships will be disqualified from involvement in the CE activity as a content developer, planner, or presenter. A complete list of individuals’ relationships with external entities is available upon request.

Full disclosure of faculty relationships will be made prior to the activity.

In support of improving patient care, National Comprehensive Cancer Network (NCCN) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians
NCCN designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses
NCCN designates this educational activity for a maximum of 1.0 contact hour.

Pharmacists
NCCN designates this application-based continuing education activity for 1.0 contact hour (0.10 CEUs) of continuing education credit. UAN: JA4008196-0000-20-086-L01-P

Physician Assistants 
NCCN has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credit. PAs should only claim credit commensurate with the extent of their participation.

 

Available for an additional fee ($49):

The Hematology/Oncology Pharmacy Association (HOPA) is accredited by the Board of Pharmacy Specialties (BPS) as a provider of board certification oncology credit (BCOP). A BCOP statement of credit will be issued only upon completion of a post-activity evaluation form and post-test, with a passing grade of 75% achieved.

Disclosure of Conflicts of Interest: The Hematology/Oncology Pharmacy Association (HOPA) assesses conflict of interest with its instructors, planners, managers, and other individuals who are in a position to control the content of CE activities. All relevant conflicts of interest that are identified are thoroughly vetted by HOPA for fair balance, scientific objectivity of studies utilized in this activity, and patient care recommendations. HOPA is committed to providing its learners with high-quality CE activities and related materials that promote improvements of quality in healthcare and not a specific proprietary business interest of a commercial interest.

Reported Areas of Conflict: Hematology/Oncology Pharmacy Association does not view the existence of relationships as an implication of bias or that the value of the material is decreased. The content of the activity was planned to be balanced, objective, and scientifically rigorous. Occasionally, authors may express opinions that represent their own viewpoint. Conclusions drawn by participants should be derived from objective analysis of scientific data. Unlabeled/unapproved uses of drugs. All faculty have indicated that they have not referenced unlabeled/unapproved uses of drugs and devices.

Available Credit

  • 1.00 AAPA Category 1 CME credit
  • 1.00 ACPE contact hours
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 ANCC contact hours
  • 1.00 Participation

Price

Cost:
$0.00
Please login or register to take this course.

Click the Take Course button to register for this live webinar.

This webinar will be presented live one time only on Tuesday, December 8, 2020, from 2:00 - 3:00 PM Eastern Standard Time (EST) (UTC -5).  To adjust for other time zones, click here.

Required Hardware/software

To complete this activity, users will need:

  • A device with an Internet connection and sound playback capability
    • One of the two latest versions of Google Chrome, Mozilla Firefox, or Safari
    • Internet Explorer is no longer supported
  • Adobe Reader or other PDF reader software for certificate viewing/printing