Most patients with endometrial cancer will present with early-stage disease.

The NCCN Guidelines Insights on Adolescent and Young Adult (AYA) Oncology discuss the fertility and endocrine issues that are relevant to the management of AYA patients with cancer.  Fertility preservation should be an essential part in the treatment of AYA patients with cancer.

Mutational testing has moved to the forefront as an integral component in the management of patients with non–small cell lung cancer (NSCLC).

Lymphoma is a well-recognized complication in patients infected with HIV. Although its incidence has declined since the advent of antiretroviral therapy, it remains higher than in the general population.

Clear evidence is available regarding the wide variation in the quality of cancer care delivered in the United States. These findings led the Institute of Medicine (IOM) in 1999 to call for major changes in cancer care delivery to improve quality and enhance the patient experience.

Hematopoietic cell transplantation (HCT) provides a life-prolonging or potentially curative treatment option for patients with hematologic malignancies.

The NCCN Guidelines for Prostate Cancer provide multidisciplinary recommendations on the clinical management of patients with prostate cancer. This report highlights notable recent updates.

No effective systemic treatment exists for malignant peripheral nerve sheath tumors (MPNSTs).

The 2013 NCCN Clinical Practice Guidelines in Oncology address the evaluation and management of patients at risk of inherited susceptibility to colorectal cancer.

Randomized trials support the use of neoadjuvant chemotherapy in muscle-invasive bladder cancer due to a noted survival advantage, which appeared to be strongly related to downstaging of the cancer to pT0 (complete pathologic response).